Papulo pustolosi o rash follicolare
Skin problems, Skin problems: Oncology

Papulo pustulosis or follicular rash in oncological treatments

What is it

In recent years, the advanced pharmaceutical industry has produced numerous biological drugs capable of defeating the tumor by blocking certain cell receptors. Some of these are already marketed, while others will be soon. The names of the most used biological drugs are Cetuximab (Erbitux), Panitumumab (Vectibix), Gefitinib (Iressa), Erlotinib (Tarceva), Trastuzumab (Herceptin), Lapatinib (Tyverb).
The papulo-pustular reaction is the most common event during treatment with EGFR inhibitors.
It occurs with the appearance of inflammatory papules or pustules at the level of hair follicles, especially in areas rich in sebaceous glands as the face and upper part of the trunk.
The reaction is sometimes violent causing plaques, crusting, pain and burning.
Papulopustular rash, or follicular rash, depending on the intensity and extent can be classified into 4 levels.

Papulo pustolosi o rash follicolare
Papulo pustolosi o rash follicolare nei trattamenti oncologici

What to do

Level 1 and 2 folliculitis usually do not require specific treatment, just avoid the irritation from washing using a solution of Potassium Permanganate for skin cleansing and applying after LENITIVE CREAM.
For the treatment of level 3 and 4 folliculitis it is recommended the use of 2S CREAM in small quantities, with a lot of massage, once a day.
For the make-up use COLOR CLAY a natural covering foundation free of water, emulsifiers, preservatives, colorants and perfumes.
To protect yourself from the sun apply SUN CLAY.
To remove make-up we recommend the use of CLEANSING CREAM because of the dryness of the skin.

Recommended products

Sun Clay


Lenitive cream


Cream 2S – with sulfur and salicylic acid


Cleansing cream


Clay Color